• 
  Argentinos – Huracan

  13 May

• 
  Belgrano – Union

  12 May

• 
  Santa Fe – America

  13 May

• 
  Atletico Nacional – Inter

  13 May

• 
  Mushuc Runa – LDU Quito

  12 May

• 
  Manchester City – Crystal

  13 May

• 
  Lens – PSG

  13 May

• 
  Brest – Strasbourg

  13 May

• 
  Red Star – Rodez

  12 May

• 
  Machida Zelvia – Tokyo

  13 May

• 
  Vissel Kobe – Kyoto

  13 May

• 
  Lokomotiv – Ak Bars

  13 May

• 
  Cerro Porteno – Guarani

  12 May

• 
  Alaves – Barcelona

  13 May

• 
  Getafe – Mallorca

  13 May

• 
  Villarreal – Sevilla

  13 May

• 
  Espanyol – Athletic

  13 May

• 
  Osasuna – Atletico

  12 May

• 
  Real Betis – Elche

  12 May

• 
  Celta – Levante

  12 May

• 
  Shakhtar – Obolon

  13 May

• 
  LNZ Cherkasy – Poltava

  13 May

• 
  Dynamo Kyiv – Kolos

  13 May

• 
  Veres – Kryvbas

  12 May

• 
  Metalist 1925 – Karpaty

  12 May

• 
  Epitsentr – Polissya

  12 May

• 
  Oleksandria – Zoria

  12 May

• 
  Cerro Largo – Penarol

  12 May

• 
  Buducnost – Cluj-Napoca

  12 May

• 
  Cedevita Olimpija – Crvena

  12 May

• 
  Quimsa – Instituto

  12 May

• 
  Obera – Boca Juniors

  12 May

• 
  San Martin T – Gimnasia

  13 May

• 
  Casper Ruud – Karen

  13 May

• 
  Thiago Tirante – Daniil

  12 May

• 
  Hamad Medjedovic – Martin

  12 May

• 
  Andrey Rublev – Nikiloz

  12 May

• 
  Jannik Sinner – Andrea

  12 May

• 
  Luciano Darderi – Alexander

  12 May

• 
  Rafael Jodar – Learner

  12 May

• 
  Lorenzo Musetti – Casper

  12 May

• 
  Karen Khachanov – Dino

  12 May

• 
  Sabah – Zira

  13 May

• 
  Londrina – Sao Bernardo

  12 May

• 
  Ludogorets – Levski

  13 May

• 
  CSKA Sofia – CSKA 1948

  13 May

• 
  Slavia Sofia – Dobrudzha

  13 May

• 
  Botev Plovdiv – Arda

  12 May

• 
  Cherno More – Lokomotiv

  12 May

• 
  Forge – Supra du Quebec

  13 May