• 
  Velez Sarsfield – Gimnasia

  11 May

• 
  River Plate – San

  10 May

• 
  Estudiantes LP – Racing

  10 May

• 
  Vasco – Athletico-PR

  11 May

• 
  Gremio-RS – Flamengo-RJ

  10 May

• 
  Mirassol – Chapecoense

  10 May

• 
  Corinthians – Sao Paolo

  10 May

• 
  Santos-SP – RB

  10 May

• 
  Remo – Palmeiras

  10 May

• 
  Atletico-MG – Botafogo-RJ

  10 May

• 
  Once Caldas – Atletico

  11 May

• 
  Mushuc Runa – LDU Quito

  12 May

• 
  Manta – Macara

  11 May

• 
  Emelec – Libertad

  10 May

• 
  Tottenham – Leeds Utd

  11 May

• 
  Le Havre – Marseille

  10 May

• 
  AS Monaco – Lille

  10 May

• 
  Angers – Strasbourg

  10 May

• 
  Toulouse – Lyon

  10 May

• 
  PSG – Brest

  10 May

• 
  Metz – Lorient

  10 May

• 
  Rennes – Paris

  10 May

• 
  Auxerre – Nice

  10 May

• 
  Napoli – Bologna

  11 May

• 
  Milan – Atalanta

  10 May

• 
  Lokomotiv – Ak Bars

  11 May

• 
  Pumas – America

  11 May

• 
  Pachuca – Toluca

  11 May

• 
  Rio Ave – Sporting

  11 May

• 
  Benfica – Braga

  11 May

• 
  Tondela – Moreirense

  11 May

• 
  Estrela – Famalicao

  11 May

• 
  Gil Vicente – Arouca

  11 May

• 
  Vitoria – Casa Pia

  11 May

• 
  Santa Clara – Nacional

  11 May

• 
  Alverca – Estoril Praia

  10 May

• 
  Metaloglobus – Hermannstadt

  11 May

• 
  Dynamo M – Krasnodar

  11 May

• 
  Spartak M – Rubin

  11 May

• 
  Nizhnyi Novgorod – CSKA

  11 May

• 
  Akron – Rostov

  11 May

• 
  Rayo Vallecano – Girona

  11 May

• 
  Barcelona – Real

  10 May

• 
  Veres – Kryvbas

  12 May

• 
  Epitsentr – Polissya

  12 May

• 
  Oleksandria – Zoria

  12 May

• 
  Cerro Largo – Penarol

  12 May

• 
  Deportivo Maldonado – Boston

  11 May

• 
  Nacional M – Cerro

  10 May

• 
  MC Torque – Progreso

  10 May